Palmitoylation of Pulmonary Surfactant Protein SP-C Is Critical for Its Functional Cooperation with SP-B to Sustain Compression/Expansion Dynamics in Cholesterol-Containing Surfactant Films

Recent data suggest that a functional cooperation between surfactant proteins SP-B and SP-C may be required to sustain a proper compression-expansion dynamics in the presence of physiological proportions of cholesterol. SP-C is a dually palmitoylated polypeptide of 4.2 kDa, but the role of acylation...

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Bibliographische Detailangaben
Hauptverfasser: Baumgart, Florian, Ospina, Olga L., Mingarro, Ismael, Rodríguez-Crespo, Ignacio, Pérez-Gil, Jesús
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2010
Schlagworte:
Membrane
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980709/
https://ncbi.nlm.nih.gov/pubmed/21081071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.08.070
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