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Pulmonary Surfactant Protein SP-C Counteracts the Deleterious Effects of Cholesterol on the Activity of Surfactant Films under Physiologically Relevant Compression-Expansion Dynamics

The presence of cholesterol is critical in defining a dynamic lateral structure in pulmonary surfactant membranes. However, an excess of cholesterol has been associated with impaired surface activity of surfactant. It has also been reported that surfactant protein SP-C interacts with cholesterol in...

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Detalhes bibliográficos
Main Authors: Gómez-Gil, Leticia, Schürch, David, Goormaghtigh, Erik, Pérez-Gil, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776298/
https://ncbi.nlm.nih.gov/pubmed/19917227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.08.045
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