Unifying Candidate Gene and GWAS Approaches in Asthma

The first genome wide association study (GWAS) for childhood asthma identified a novel major susceptibility locus on chromosome 17q21 harboring the ORMDL3 gene, but the role of previous asthma candidate genes was not specifically analyzed in this GWAS. We systematically identified 89 SNPs in 14 cand...

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Main Authors: Michel, Sven, Liang, Liming, Depner, Martin, Klopp, Norman, Ruether, Andreas, Kumar, Ashish, Schedel, Michaela, Vogelberg, Christian, von Mutius, Erika, von Berg, Andrea, Bufe, Albrecht, Rietschel, Ernst, Heinzmann, Andrea, Laub, Otto, Simma, Burkhard, Frischer, Thomas, Genuneit, Jon, Gut, Ivo G., Schreiber, Stefan, Lathrop, Mark, Illig, Thomas, Kabesch, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980484/
https://ncbi.nlm.nih.gov/pubmed/21103062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013894
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