Osteopontin Is Required for the Early Onset of High Fat Diet-Induced Insulin Resistance in Mice

BACKGROUND: Insulin resistance is manifested in muscle, adipose tissue, and liver and is associated with adipose tissue inflammation. The cellular components and mechanisms that regulate the onset of diet-induced insulin resistance are not clearly defined. METHODOLOGY AND PRINCIPAL FINDINGS: We init...

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Hlavní autoři: Chapman, Justin, Miles, Philip D., Ofrecio, Jachelle M., Neels, Jaap G., Yu, Joseph G., Resnik, Jamie L., Wilkes, Jason, Talukdar, Saswata, Thapar, Divya, Johnson, Kristen, Sears, Dorothy D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980483/
https://ncbi.nlm.nih.gov/pubmed/21103061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013959
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