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Glucose-induced ERM protein activation and translocation regulates insulin secretion
A key step in regulating insulin secretion is insulin granule trafficking to the plasma membrane. Using live-cell time-lapse confocal microscopy, we observed a dynamic association of insulin granules with filamentous actin and PIP2-enriched structures. We found that the scaffolding protein family ER...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2980361/ https://ncbi.nlm.nih.gov/pubmed/20739507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00199.2010 |
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