Disease tropism of c-erbB: effects of carboxyl-terminal tyrosine and internal mutations on tissue-specific transformation.

Avian leukosis virus induces erythroleukemia in chickens by proviral insertional mutation of the protooncogene c-erbB. The product of the insertionally activated c-erbB locus lacks the extracellular ligand-binding domain and is strictly leukemogenic. It has previously been demonstrated that the dise...

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Detaylı Bibliyografya
Asıl Yazarlar: Pelley, R J, Maihle, N J, Boerkoel, C, Shu, H K, Carter, T H, Moscovici, C, Kung, H J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1989
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC298016/
https://ncbi.nlm.nih.gov/pubmed/2550929
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