Disease tropism of c-erbB: effects of carboxyl-terminal tyrosine and internal mutations on tissue-specific transformation.

Avian leukosis virus induces erythroleukemia in chickens by proviral insertional mutation of the protooncogene c-erbB. The product of the insertionally activated c-erbB locus lacks the extracellular ligand-binding domain and is strictly leukemogenic. It has previously been demonstrated that the dise...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Pelley, R J, Maihle, N J, Boerkoel, C, Shu, H K, Carter, T H, Moscovici, C, Kung, H J
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1989
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298016/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2550929/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.18.7164
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