PAX3 and SOX10 activate MET receptor expression in melanoma

Melanoma is a cancer with a poorly understood molecular pathobiology. We find the transcription factors PAX3, SOX10, MITF, and the tyrosine kinase receptor MET expressed in melanoma cell lines and primary tumors. Analysis for MET expression in primary tumor specimens showed 27/40 (68%) of the sample...

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Bibliografiske detaljer
Main Authors: Mascarenhas, Joseph B., Littlejohn, Erica L., Wolsky, Rebecca J., Young, Kacey P, Nelson, Maria, Salgia, Ravi, Lang, Deborah
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2979310/
https://ncbi.nlm.nih.gov/pubmed/20067553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2010.00667.x
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