PAX6 Is Expressed in Pancreatic Cancer and Actively Participates in Cancer Progression through Activation of the MET Tyrosine Kinase Receptor Gene

Tumors of the exocrine pancreas have a poor prognosis. Several proteins are overexpressed in this cancer type, including the MET tyrosine kinase receptor and the transcription factor PAX6. In this report, we find that PAX6(5a), an alternately spliced variant form of PAX6, is expressed in pancreatic...

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Autors principals: Mascarenhas, Joseph B., Young, Kacey P., Littlejohn, Erica L., Yoo, Brian K., Salgia, Ravi, Lang, Deborah
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Transcription, Chromatin, and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785681/
https://ncbi.nlm.nih.gov/pubmed/19651775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.047209
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