The octamer motif is a B-lymphocyte-specific regulatory element of the HLA-DR alpha gene promoter.

The human class II gene, HLA-DR alpha, contains an octanucleotide sequence ATTTGCAT located approximately 40 base pairs upstream of the transcription initiation site. We have investigated the transcriptional function of the DR alpha octamer in human B-lymphoblastoid cells and non-B cells. Deletion a...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Sherman, P A, Basta, P V, Heguy, A, Wloch, M K, Roeder, R G, Ting, J P
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1989
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297921/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2505259/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.17.6739
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