The octamer motif is a B-lymphocyte-specific regulatory element of the HLA-DR alpha gene promoter.
The human class II gene, HLA-DR alpha, contains an octanucleotide sequence ATTTGCAT located approximately 40 base pairs upstream of the transcription initiation site. We have investigated the transcriptional function of the DR alpha octamer in human B-lymphoblastoid cells and non-B cells. Deletion a...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1989
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297921/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2505259/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.17.6739 |
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