Surface immunoglobulin-mediated B-cell activation in the absence of detectable elevations in intracellular ionized calcium: a model for T-cell-independent B-cell activation.

We recently showed that anti-immunoglobulin conjugated to high molecular weight dextran is 1000-fold more mitogenic for B cells than unconjugated anti-immunoglobulin. This system serves as a model for T-cell-independent type 2 antigens such as haptenated Ficoll, dextran, and bacterial polysaccharide...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Brunswick, M, June, C H, Finkelman, F D, Dintzis, H M, Inman, J K, Mond, J J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297918/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2549544/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.17.6724
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