Surface immunoglobulin-mediated B-cell activation in the absence of detectable elevations in intracellular ionized calcium: a model for T-cell-independent B-cell activation.

We recently showed that anti-immunoglobulin conjugated to high molecular weight dextran is 1000-fold more mitogenic for B cells than unconjugated anti-immunoglobulin. This system serves as a model for T-cell-independent type 2 antigens such as haptenated Ficoll, dextran, and bacterial polysaccharide...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Brunswick, M, June, C H, Finkelman, F D, Dintzis, H M, Inman, J K, Mond, J J
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1989
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297918/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2549544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.17.6724
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