Nalaganje...

The noncovalent complex between DNA and the bifunctional intercalator ditercalinium is a substrate for the UvrABC endonuclease of Escherichia coli.

We have demonstrated that the noncovalent complex formed between DNA and an antitumor bifunctional intercalator, ditercalinium, is recognized in vitro as bulky covalent DNA lesions by the purified Escherichia coli UvrABC endonuclease. It was established that no covalent drug-DNA adduct was formed du...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Lambert, B, Jones, B K, Roques, B P, Le Pecq, J B, Yeung, A T
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1989
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297883/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2671994/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.17.6557
Oznake: Označite
Brez oznak, prvi označite!