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MicroRNA-21 Over-Expression Contributes to Vestibular Schwannoma Cell Proliferation and Survival
HYPOTHESIS: Elevated levels of hsa-microRNA-21 (miR-21) in vestibular schwannomas (VSs) may contribute to tumor growth by down-regulating the tumor suppressor gene phosphatase and tensin homolog (PTEN) and consequent hyperactivation of protein kinase B (AKT), a key signaling protein in the cellular...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2978772/ https://ncbi.nlm.nih.gov/pubmed/20856158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MAO.0b013e3181f20655 |
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