Loading...

Characterization of a Novel SOD-1(G93A) Transgenic Mouse Line with Very Decelerated Disease Development

Amyotrophic Lateral Sclerosis (ALS) is a fatal motoneuron disease, characterized by progressive weakness, muscle wasting and death ensuing 3–5 years after diagnosis. The etiology of ALS is complex and therapeutic approaches rely mostly on transgenic animal models with SOD-1 mutations. Most frequentl...

Full description

Saved in:
Bibliographic Details
Main Authors: Henriques, Alexandre, Pitzer, Claudia, Schneider, Armin
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978730/
https://ncbi.nlm.nih.gov/pubmed/21102999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015445
Tags: Add Tag
No Tags, Be the first to tag this record!