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Transient Increase in Cyclic AMP Localized to Macrophage Phagosomes

Cyclic AMP (cAMP) regulates many biological processes and cellular functions. The importance of spatially localized intracellular gradients of cAMP is increasingly appreciated. Previous work in macrophages has shown that cAMP is produced during phagocytosis and that elevated cAMP levels suppress hos...

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Detalhes bibliográficos
Main Authors: Ballinger, Megan N., Welliver, Timothy, Straight, Samuel, Peters-Golden, Marc, Swanson, Joel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978719/
https://ncbi.nlm.nih.gov/pubmed/21085604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013962
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