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SHIP-1 Increases Early Oxidative Burst and Regulates Phagosome Maturation in Macrophages: SHIP-1 regulates macrophage oxidase activity
Although the inositol phosphatase SHIP-1 is generally thought to inhibit signaling for Fc receptor-mediated phagocytosis, the product of its activity, phosphatidylinositol 3,4 bisphosphate (PI(3,4)P(2)) has been implicated in activation of the NADPH oxidase. This suggests that SHIP-1 positively regu...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2913413/ https://ncbi.nlm.nih.gov/pubmed/18490750 |
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