Preclinical Deposition of Pathological Prion Protein in Muscle of Experimentally Infected Primates

Prion diseases are transmissible fatal neurodegenerative disorders affecting humans and animals. A central step in disease progression is the accumulation of a misfolded form (PrP(Sc)) of the host encoded prion protein (PrP(C)) in neuronal and non-neuronal tissues. The involvement of peripheral tiss...

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Bibliografiske detaljer
Main Authors: Krasemann, Susanne, Neumann, Melanie, Geissen, Markus, Bodemer, Walter, Kaup, Franz-Josef, Schulz-Schaeffer, Walter, Morel, Nathalie, Aguzzi, Adriano, Glatzel, Markus
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978702/
https://ncbi.nlm.nih.gov/pubmed/21085647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013906
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