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Insight into the Mechanism of Human Herpesvirus 7 U21-mediated Diversion of Class I MHC Molecules to Lysosomes

The U21 open reading frame from human herpesvirus-7 encodes a membrane protein that associates with and redirects class I MHC molecules to the lysosomal compartment. The mechanism by which U21 accomplishes this trafficking excursion is unknown. Here we have examined the contribution of localization,...

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Hlavní autoři: Glosson, Nicole L., Gonyo, Patrick, May, Nathan A., Schneider, Christine L., Ristow, Laura C., Wang, Qiuhong, Hudson, Amy W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978630/
https://ncbi.nlm.nih.gov/pubmed/20833720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.125849
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