Identification of Ypk1 as a Novel Selective Substrate for Nitrogen Starvation-triggered Proteolysis Requiring Autophagy System and Endosomal Sorting Complex Required for Transport (ESCRT) Machinery Components

Nitrogen starvation-mediated reduction of Ypk1 is suggested to suppress translational initiation, possibly in parallel with the target of rapamycin complex 1 (TORC1) signaling. However, the molecular mechanism that regulates Ypk1 in nitrogen-starved cells is poorly understood. Here we report that Yp...

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Bibliographic Details
Main Authors: Shimobayashi, Mitsugu, Takematsu, Hiromu, Eiho, Kazuo, Yamane, Yukari, Kozutsumi, Yasunori
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Protein Synthesis and Degradation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978627/
https://ncbi.nlm.nih.gov/pubmed/20855891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.119180
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