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Intragenic Suppressing Mutations Correct the Folding and Intracellular Traffic of Misfolded Mutants of Yor1p, a Eukaryotic Drug Transporter

ATP-binding cassette (ABC) transporters play pivotal physiological roles in substrate transport across membranes, and defective assembly of these proteins can cause severe disease associated with improper drug or ion flux. The yeast protein Yor1p is a useful model to study the biogenesis of ABC tran...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pagant, Silvere, Halliday, John J., Kougentakis, Christos, Miller, Elizabeth A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978558/
https://ncbi.nlm.nih.gov/pubmed/20837481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.142760
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