Intracerebroventricular infusion of interleukin 1 rapidly decreases peripheral cellular immune responses.

Low doses (50-200 pg or 3.1-12.4 fmol) of interleukin 1 (IL-1) infused into the brain of rats produced rapid suppression of various cellular immune responses in peripheral lymphocytes of rats. Fifteen minutes after infusion of purified IL-1 beta into the lateral ventricle, natural killer cell activi...

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Detalhes bibliográficos
Main Authors: Sundar, S K, Becker, K J, Cierpial, M A, Carpenter, M D, Rankin, L A, Fleener, S L, Ritchie, J C, Simson, P E, Weiss, J M
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC297847/
https://ncbi.nlm.nih.gov/pubmed/2548213
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