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Efficient production of recombinant IgG by metabolic control and co-expression with GLUT5 in a fructose-based medium
A fructose-based cell culture is suitable for the process control of protein production because of slow sugar consumption rate and low lactate accumulation. The fructose transporter, GLUT5, mediates its incorporation into cells and is required for the fructose-based culture. In order to produce effi...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Springer Netherlands
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2978310/ https://ncbi.nlm.nih.gov/pubmed/20697810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-010-9289-6 |
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