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Expression and purification of ELP-intein-tagged target proteins in high cell density E. coli fermentation

BACKGROUND: Elastin-like polypeptides (ELPs) are useful tools that can be used to non-chromatographically purify proteins. When paired with self-cleaving inteins, they can be used as economical self-cleaving purification tags. However, ELPs and ELP-tagged target proteins have been traditionally expr...

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Détails bibliographiques
Auteurs principaux: Fong, Baley A, Wood, David W
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978133/
https://ncbi.nlm.nih.gov/pubmed/20959011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-9-77
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