Levodopa-Induced Dyskinesia Is Associated with Increased Thyrotropin Releasing Hormone in the Dorsal Striatum of Hemi-Parkinsonian Rats

BACKGROUND: Dyskinesias associated with involuntary movements and painful muscle contractions are a common and severe complication of standard levodopa (L-DOPA, L-3,4-dihydroxyphenylalanine) therapy for Parkinson's disease. Pathologic neuroplasticity leading to hyper-responsive dopamine recepto...

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Detalhes bibliográficos
Main Authors: Cantuti-Castelvetri, Ippolita, Hernandez, Ledia F., Keller-McGandy, Christine E., Kett, Lauren R., Landy, Alex, Hollingsworth, Zane R., Saka, Esen, Crittenden, Jill R., Nillni, Eduardo A., Young, Anne B., Standaert, David G., Graybiel, Ann M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978093/
https://ncbi.nlm.nih.gov/pubmed/21085660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013861
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