Histone Deacetylases and the Nuclear Receptor Corepressor Regulate Lytic-Latent Switch Gene 50 in Murine Gammaherpesvirus 68-Infected Macrophages

Gammaherpesviruses are important oncogenic pathogens that transit between lytic and latent life cycles. Silencing the lytic gene expression program enables the establishment of latency and a lifelong chronic infection of the host. In murine gammaherpesvirus 68 (MHV68, γHV68), essential lytic switch...

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Hlavní autoři: Goodwin, Megan M., Molleston, Jerome M., Canny, Susan, Abou El Hassan, Mohamed, Willert, Erin K., Bremner, Rod, Virgin, Herbert W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2977890/
https://ncbi.nlm.nih.gov/pubmed/20719946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00396-10
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