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Murine Gammaherpesvirus 68 Has Evolved Gamma Interferon and Stat1-Repressible Promoters for the Lytic Switch Gene 50

Cytokines regulate viral gene expression with important consequences for viral replication and pathogenesis. Gamma interferon (IFN-γ) is a key regulator of chronic murine gammaherpesvirus 68 (γHV68) infection and a potent inhibitor of γHV68 reactivation from latency. Macrophages are the cell type th...

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Bibliografiske detaljer
Main Authors: Goodwin, Megan M., Canny, Susan, Steed, Ashley, Virgin, Herbert W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838114/
https://ncbi.nlm.nih.gov/pubmed/20071569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02099-09
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