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Herpes Simplex Virus Glycoprotein D Interferes with Binding of Herpesvirus Entry Mediator to Its Ligands through Downregulation and Direct Competition

To initiate membrane fusion and virus entry, herpes simplex virus (HSV) gD binds to a cellular receptor such as herpesvirus entry mediator (HVEM). HVEM is a tumor necrosis factor (TNF) receptor family member with four natural ligands that either stimulate (LIGHT and LTα) or inhibit (BTLA and CD160)...

詳細記述

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書誌詳細
主要な著者: Stiles, Katie M., Whitbeck, J. Charles, Lou, Huan, Cohen, Gary H., Eisenberg, Roselyn J., Krummenacher, Claude
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2977867/
https://ncbi.nlm.nih.gov/pubmed/20826693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01550-10
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