Novel Immunodominant Peptide Presentation Strategy: a Featured HLA-A*2402-Restricted Cytotoxic T-Lymphocyte Epitope Stabilized by Intrachain Hydrogen Bonds from Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Protein

Antigenic peptides recognized by virus-specific cytotoxic T lymphocytes (CTLs) are presented by major histocompatibility complex (MHC; or human leukocyte antigen [HLA] in humans) molecules, and the peptide selection and presentation strategy of the host has been studied to guide our understanding of...

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Autores principales: Liu, Jun, Wu, Peng, Gao, Feng, Qi, Jianxun, Kawana-Tachikawa, Ai, Xie, Jing, Vavricka, Christopher J., Iwamoto, Aikichi, Li, Taisheng, Gao, George F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2977860/
https://ncbi.nlm.nih.gov/pubmed/20844028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01464-10
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