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Dissection of functional domains of adenovirus DNA polymerase by linker-insertion mutagenesis.

Linker-insertion mutations were introduced into the cloned adenovirus DNA polymerase gene and the functional effects on the initiation and elongation of DNA in vitro were measured. Essential regions of the polymerase appear to be scattered in patches across the entire molecule and are not limited to...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Chen, M, Horwitz, M S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297786/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2548198/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.16.6116
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