Dissection of functional domains of adenovirus DNA polymerase by linker-insertion mutagenesis.
Linker-insertion mutations were introduced into the cloned adenovirus DNA polymerase gene and the functional effects on the initiation and elongation of DNA in vitro were measured. Essential regions of the polymerase appear to be scattered in patches across the entire molecule and are not limited to...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1989
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297786/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2548198/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.16.6116 |
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