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Hypercholesterolemia in rats impairs the cholinergic system and leads to memory deficits

Alzheimer's disease (AD) is a chronic brain disorder characterized by cognitive impairment, cholinergic dysfunction, inflammation, tau and beta-amyloid pathology and vascular damage. Recent studies have shown, that high cholesterol levels are linked to the pathology of AD. The aim of our presen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ullrich, Celine, Pirchl, Michael, Humpel, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Academic Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2977849/
https://ncbi.nlm.nih.gov/pubmed/20696249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2010.08.001
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