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Effects of Cholesterol and Its 24S-OH and 25-OH Oxysterols on Choline Acetyltransferase-Positive Neurons in Brain Slices

In Alzheimer’s disease (AD) neurons expressing the enzyme choline acetyltransferase (ChAT) degenerate and a loss of cholinergic activity directly correlates with cognitive decline. Recent studies have suggested that cholesterol plays a role in AD. The aim of the present study was to explore if chole...

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Bibliographic Details
Published in:Pharmacology
Main Authors: Ullrich, Celine, Pirchl, Michael, Humpel, Christian
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311142/
https://ncbi.nlm.nih.gov/pubmed/20571288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000314333
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