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Rapid screening of a human genomic library in yeast artificial chromosomes for single-copy sequences.

A yeast artificial chromosome (YAC) library in Saccharomyces cerevisiae consisting of 30,000 clones with an average insert size of 0.1 megabase pair of human DNA has been generated from primary fibroblast DNA. A YAC vector was modified to enable the recovery of both ends of a human DNA insert in pla...

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Detalhes bibliográficos
Main Authors: Traver, C N, Klapholz, S, Hyman, R W, Davis, R W
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC297738/
https://ncbi.nlm.nih.gov/pubmed/2668948
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