Enzymes work by solvation substitution rather than by desolvation.
Considerable attention has recently been drawn to the hypothesis that enzymes catalyze their reactions by displacing solvent and creating an environment similar to the gas phase for the reacting substrates. This "desolvation hypothesis" is reexamined in this paper by defining a common reference ener...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1989
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297722/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2762299/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.15.5820 |
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