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Effect of Drug Solubility on Polymer Hydration and Drug Dissolution from Polyethylene Oxide (PEO) Matrix Tablets

The purpose of the study was to investigate the effect of drug solubility on polymer hydration and drug dissolution from modified release matrix tablets of polyethylene oxide (PEO). Different PEO matrix tablets were prepared using acetaminophen (ACE) and ibuprofen (IBU) as study compounds and Polyox...

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Detalhes bibliográficos
Main Authors: Li, Hongtao, Hardy, Robert J., Gu, Xiaochen
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976924/
https://ncbi.nlm.nih.gov/pubmed/18431663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-008-9060-x
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