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Effect of Drug Solubility on Polymer Hydration and Drug Dissolution from Polyethylene Oxide (PEO) Matrix Tablets

The purpose of the study was to investigate the effect of drug solubility on polymer hydration and drug dissolution from modified release matrix tablets of polyethylene oxide (PEO). Different PEO matrix tablets were prepared using acetaminophen (ACE) and ibuprofen (IBU) as study compounds and Polyox...

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Bibliografiske detaljer
Main Authors: Li, Hongtao, Hardy, Robert J., Gu, Xiaochen
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976924/
https://ncbi.nlm.nih.gov/pubmed/18431663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-008-9060-x
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