Preformulation Considerations for Controlled Release Dosage Forms: Part II—Selected Candidate Support

Practical examples of preformulation support of the form selected for formulation development are provided using several drug substances (DSs). The examples include determination of the solubilities vs. pH particularly for the range pH 1 to 8 because of its relationship to gastrointestinal (GI) cond...

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Detalhes bibliográficos
Autor principal: Chrzanowski, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2008
Assuntos:
Research Article/Themed Issue: Oral Controlled Release Development and Technology Guest Editors: Stephen A. Howard and Jian-Xin
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976920/
https://ncbi.nlm.nih.gov/pubmed/18431656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-008-9067-3
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