Evidence that brain prostaglandin E2 is involved in physiological sleep-wake regulation in rats.

We reported in previous studies that prostaglandin E2 (PGE2) has central effects of augmenting wakefulness and suppressing slow-wave sleep (SWS) and paradoxical sleep (PS) in rats. In the present study, we tested the effect of AH 6809, an antagonist of PGE2 receptors, on sleep-wake activities. AH 68...

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Bibliographic Details
Main Authors: Matsumura, H, Honda, K, Choi, W S, Inoué, S, Sakai, T, Hayaishi, O
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC297685/
https://ncbi.nlm.nih.gov/pubmed/2748610
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