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The C-Terminal of Nucleolin Promotes the Formation of the c-MYC G-Quadruplex and Inhibits c-MYC Promoter Activity

Nucleolin, the most abundant nucleolar phosphoprotein of eukaryotic cells, is known primarily for its role in ribosome biogenesis and cell proliferation. It is, however, a multifunctional protein that, depending on the cellular context, can drive either cell proliferation or apoptosis. Our laborator...

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Detalhes bibliográficos
Main Authors: González, Verónica, Hurley, Laurence H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976822/
https://ncbi.nlm.nih.gov/pubmed/20932061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100509s
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