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Beryllium sulfate induces p21(CDKN1A) expression and a senescence-like cell cycle arrest in susceptible cancer cell types
In fibroblasts, beryllium salt causes activation of the p53 transcription factor and induction of a senescence-like state. It is not known whether Be(2+) can affect the proliferation of cancer cells, which are generally unsusceptible to senescence. A172 glioblastoma and RKO colon carcinoma cell line...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2976805/ https://ncbi.nlm.nih.gov/pubmed/20549306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10534-010-9352-y |
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