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Vimentin contributes to changes in chondrocyte stiffness in osteoarthritis

Actin and tubulin cytoskeletal components are studied extensively in chondrocytes, but less is known about vimentin intermediate filaments. In other cell types, vimentin is a determinant of cell stiffness and disruption of vimentin networks weakens the mechanical integrity of cells. Changes in vimen...

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Bibliographic Details
Main Authors: Haudenschild, Dominik R., Chen, Jianfen, Pang, Nina, Steklov, Nikolai, Grogan, Shawn P., Lotz, Martin K., D’Lima, Darryl D.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976780/
https://ncbi.nlm.nih.gov/pubmed/20602472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.21198
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