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Rho Kinase-Dependent Sox9 Activation in Chondrocytes

OBJECTIVE: The transcription factor Sox9, directly regulates the expression of the major proteoglycans and collagens comprising the cartilage extracellular matrix. The DNA-binding activity and cellular localization of Sox9 is controlled through posttranslational modifications including phosphorylati...

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Autores principales: Haudenschild, Dominik R., Chen, Jianfen, Pang, Nina, Lotz, Martin K., D’Lima, Darryl D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935318/
https://ncbi.nlm.nih.gov/pubmed/20039424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.25051
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