Alternative splicing and nonsense-mediated decay regulate telomerase reverse transcriptase (TERT) expression during virus-induced lymphomagenesis in vivo

BACKGROUND: Telomerase activation, a critical step in cell immortalization and oncogenesis, is partly regulated by alternative splicing. In this study, we aimed to use the Marek's disease virus (MDV) T-cell lymphoma model to evaluate TERT regulation by splicing during lymphomagenesis in vivo, f...

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Detalhes bibliográficos
Main Authors: Amor, Souheila, Remy, Sylvie, Dambrine, Ginette, Le Vern, Yves, Rasschaert, Denis, Laurent, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976754/
https://ncbi.nlm.nih.gov/pubmed/20964812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-571
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