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Thermodynamic Analysis of Nylon Nucleic Acids
The stability and structure of nylon nucleic acid duplexes with complementary DNA and RNA strands was examined. Thermal denaturing studies of a series of oligonucleotides containing nylon nucleic acids (1 to 5 amide linkages) revealed that the amide linkage enhanced significantly the binding affinit...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2976662/ https://ncbi.nlm.nih.gov/pubmed/18543259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200800032 |
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