Thermodynamic Analysis of Nylon Nucleic Acids

The stability and structure of nylon nucleic acid duplexes with complementary DNA and RNA strands was examined. Thermal denaturing studies of a series of oligonucleotides containing nylon nucleic acids (1 to 5 amide linkages) revealed that the amide linkage enhanced significantly the binding affinit...

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Hlavní autoři: Liu, Yu, Wang, Risheng, Ding, Liang, Sha, Ruojie, Lukeman, Philip S., Canary, James W., Seeman, Nadrian C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976662/
https://ncbi.nlm.nih.gov/pubmed/18543259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200800032
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