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Structure of the human retinoblastoma gene.

Complete inactivation of the human retinoblastoma gene (RB) is believed to be an essential step in tumorigenesis of several different cancers. To provide a framework for understanding inactivation mechanisms, the structure of RB was delineated. The RB transcript is encoded in 27 exons dispersed over...

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Autori principali: Hong, F D, Huang, H J, To, H, Young, L J, Oro, A, Bookstein, R, Lee, E Y, Lee, W H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1989
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC297651/
https://ncbi.nlm.nih.gov/pubmed/2748600
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