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Mono-hydroxy methoxychlor alters levels of key sex steroids and steroidogenic enzymes in cultured mouse antral follicles

Methoxychlor (MXC) is an organochlorine pesticide that reduces fertility in female rodents by decreasing antral follicle numbers and increasing follicular death. MXC is metabolized in the body to mono-hydroxy MXC (mono-OH). Little is known about the effects of mono-OH on the ovary. Thus, this work t...

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Detalhes bibliográficos
Main Authors: Craig, Zelieann R., Leslie, Traci C., Hatfield, Kimberly P., Gupta, Rupesh K., Flaws, Jodi A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976486/
https://ncbi.nlm.nih.gov/pubmed/20840852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2010.09.001
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