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Co-treatment of mouse antral follicles with 17β-estradiol interferes with mono-2-ethylhexyl phthalate (MEHP)-induced atresia and altered apoptosis gene expression

Mono-2-ethyhexyl phthalate (MEHP) is a metabolite of a plasticizer found in many consumer products. MEHP inhibits mouse ovarian follicle growth by reducing 17β-estradiol (E(2)) production. Yet, whether MEHP causes follicle death (atresia) is unclear. We hypothesized that MEHP causes atresia by alter...

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Detalhes bibliográficos
Main Authors: Craig, Zelieann R., Singh, Jeffrey, Gupta, Rupesh K., Flaws, Jodi A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028413/
https://ncbi.nlm.nih.gov/pubmed/24412242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2014.01.002
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