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Sequence Evolution of HIV-1 following Mother-to-Child Transmission

The genetic heterogeneity of HIV-1 poses a major obstacle to vaccine development. Although most horizontally acquired HIV-1 infections are initiated by a single homogeneous virus, marked genetic diversification and evolution occur following transmission. The relative contribution of the antiviral im...

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Autori principali: Ryland, Elizabeth G., Tang, Yanhua, Christie, Celia D., Feeney, Margaret E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976410/
https://ncbi.nlm.nih.gov/pubmed/20861265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01617-10
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